Patent · US Active

Device method of making, separating, and purifying artepillin C in propolis

US9517998B1 · kind B1 · utility

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9Claims
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Key dates

Filing dateDec 11, 2015
Grant dateDec 13, 2016
Priority date
Expiry dateDec 11, 2035

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/54
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A method of making, separating, and purifying artepillin C in propolis includes mixing propolis with ethanol to obtain a propolis-ethanol extract; providing supercritical carbon dioxide and the propolis-ethanol extract to a chromatographic column to separate wax, artepillin C, and flavonoids; providing supercritical carbon dioxide, the artepillin C, and the flavonoids to an adsorption column to remove the flavonoids; keeping the adsorption column still; and providing ethanol to the adsorption column to obtain the purified artepillin C.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.