Patent · US Active

Synthesis of chiral enaminones, their derivatives, and bioactivity studies thereof

US9518034B2 · kind B2 · utility

8Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 14, 2014
Grant dateDec 13, 2016
Priority date
Expiry dateJun 10, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/88
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention provides enantioenriched heterocyclic enaminone compounds with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I):comprising treating a compound of formula (II):with a transition metal catalyst under alkylation conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.