High-throughput sequencing method for methylated DNA and use thereof
US9518295B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 11, 2010 |
| Grant date | Dec 13, 2016 |
| Priority date | — |
| Expiry date | Aug 11, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a high-throughput sequencing method for methylated DNA, and use thereof. Particularly, the present invention provides a high-throughput sequencing method for methylated DNA, which combines methylated DNA immunoprecipitation, removal of repetitive sequences, and bisulfite treatment. The site of sequencing library will be decreased, and the cost will be reduced by using the method disclosed in the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.