Patent · US Active

Method for improving the properties of amphiphile particles

US9522377B2 · kind B2 · utility

0Cited by

7References

11Claims

0Family size

Assignee

CAMURUS AB · SE

Inventors

Gert Wörle · Bielefeld, DE
Fredrik Tiberg · Lund, SE
Markus Johnsson · Lund, SE
Heike Bunjes · Jena, DE
Britta Siekmann · Lomma, SE
Justas Barauskas · Lund, SE

Key dates

Filing date	Aug 4, 2004
Grant date	Dec 20, 2016
Priority date	—
Expiry date	May 10, 2030

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J13/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a method for forming a dispersion comprising non-lamellar amphiphile particles having improved phase behavior, particle size distribution and/or storage stability, said method comprising forming a dispersion of lamellar and optionally non-lamellar particles comprising at least one structuring agent in a polar solvent, heating said particles to an elevated temperature, followed by cooling, wherein said heating is to a temperature and for a period sufficient to provide, after cooling, a measurable improvement in phase behavior, particle size distribution and/or storage stability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.