Tetrahydroprotoberbine compounds and uses thereof in the treatment of neurological, psychiatric and neurodegenerative diseases
US9526721B2 · kind B2 · utility
2Cited by
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12Claims
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Inventors
Key dates
| Filing date | Aug 2, 2012 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Aug 2, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds include d-govadine, l-govadine and racemic govadine, as well as d-THPBs of general formula (I). Enantioselective processes for preparing compounds of formula (I), and d- and l-govadine are also provided.(I)
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.