Multidomain peptides for promoting angiogenesis
US9526762B1 · kind B1 · utility
4Cited by
9References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2014 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Aug 8, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/412
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides a composition comprising a multi-domain peptide capable of self-assembly into a nanofibrous hydrogel structure capable of stimulating a robust angiogenic response. In one embodiment, the composition comprises a short 15 amino acid VEGF-165 peptide mimic conjugated to a 16 amino acid multidomain peptide. A method for promoting angiogenesis and/or treating ischemic wounds in a subject is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.