Crystal form VII of agomelatine, preparation method and use thereof and pharmaceutical composition containing same
US9527803B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Mar 22, 2012 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Mar 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C231/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.