Patent · US Active

Modified variable domain molecules and methods for producing them

US9527908B2 · kind B2 · utility

0Cited by

0References

8Claims

0Family size

Assignee

Garvan Institute of Medical Research · AU

Inventors

Daniel Christ · Sydney, AU
Kip Dudgeon · Sydney, AU
Romain Rouet · Berkeley, US

Key dates

Filing date	Oct 15, 2013
Grant date	Dec 27, 2016
Priority date	—
Expiry date	Oct 15, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides an isolated, engineered or non-naturally occurring protein comprising an antibody light chain variable domain (VL) which may comprise at least one negatively charged amino acid positioned between residues 49 to 56 according to the numbering system of Kabat, the protein capable of binding specifically to an antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.