Methods for eliminating at least a substantial portion of a clonal antigen-specific memory T cell subpopulation
US9528088B2 · kind B2 · utility
24Cited by
106References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 21, 2013 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Nov 21, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to methods for stimulating T cells, and more particularly, to methods to eliminate undesired (e.g., autoreactive, alloreactive, pathogenic) subpopulations of T cells from a mixed population of T cells, thereby restoring the normal immune repertoire of said T cells. The present invention also relates to compositions of cells, including stimulated T cells having restored immune repertoire and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.