Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
US9528126B2 · kind B2 · utility
35Cited by
5References
11Claims
0Family size
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Key dates
| Filing date | Feb 7, 2012 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Dec 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.