Optimization of nucleation and crystallization for lyophilization using gap freezing
US9528761B2 · kind B2 · utility
8Cited by
24References
22Claims
0Family size
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Key dates
| Filing date | Apr 20, 2015 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Jun 22, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/68
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously and at approximately the same rate. The as frozen solution can then provide a lyophilized cake of the solutes with large and uniform pores.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.