Diagnostic and therapeutic application of CTL and NK functionally selected cells
US9528981B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Apr 12, 2007 |
| Grant date | Dec 27, 2016 |
| Priority date | — |
| Expiry date | Aug 30, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/505
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention proposes a novel therapeutic and diagnostic methodology based on the use of effector cells (for example CTL and NK cells) selected for being able to induce lysis in target cells. In particular, the invention teaches how to select strains of effector cells of the immune system according to their lytic properties. It also teaches how diagnostic procedures for checking the activity of therapeutic vaccines can be improved with respect to what shown. Finally, it shows how cell therapies used at present can be improved by using this approach.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.