Nanostructure suitable for sequestering cholesterol and other molecules
US9532948B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 15, 2012 |
| Grant date | Jan 3, 2017 |
| Priority date | — |
| Expiry date | Oct 15, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1271
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Articles, compositions, kits, and methods relating to nanostructures, including those that can sequester molecules such as cholesterol, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanoparticle core may be surrounded by a shell including a material, such as a lipid bilayer, that can interact with cholesterol and/or other lipids. In some embodiments, the structures, when introduced into a subject, can sequester cholesterol and/or other lipids and remove them from circulation. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions, especially those associated with abnormal lipid levels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.