Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes
US9533037B2 · kind B2 · utility
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5References
17Claims
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Inventors
Key dates
| Filing date | Oct 16, 2008 |
| Grant date | Jan 3, 2017 |
| Priority date | — |
| Expiry date | Jan 26, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as vaccines, such DSP synthesized according to a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use as a vaccine, preferably for infectious agents that are immune evasive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.