Alkylamidothiazoles, cosmetic or dermatological preparations containing said alkylamidothiazoles, and use thereof to combat or prevent undesired pigmentation of the skin

US9533963B2 · kind B2 · utility

Assignee

• BEIERSDORF AG · DE

Inventors

• Ludger Kolbe · Tostedt, DE
• Cathrin Scherner · Norderstedt, DE
• Sabrina Breitkreutz · Hamburg, DE
• Michael Woehrmann · Hamburg, DE
• Tobias Mann · Ann Arbor, US
• Wolfram Gerwat · Hamburg, DE
• Torsten Schlaeger · Hamburg, DE

Key dates

• Filing date: Sep 18, 2012
• Grant date: Jan 3, 2017
• Expiry date: Feb 27, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D277/48
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Alkylamidothiazoles of general formula (I), wherein R 1=—C1-C24 alkyl (linear and branched), —C1-C24 alkenyl (linear and branched), —C1-C8 cycloalkyl, —C1-C8 cycloalkyl-alkylhydroxy, —C1-C24 alkylhydroxy (linear and branched), —C1-C24 alkylamine (linear and branched), —C1-C24 alkylaryl (linear and branched), —C1-C24 alkylaryl-alkyl-hydroxy (linear and branched), —C1-C24 alkyl-heteroaryl (linear and branched), —C1-C24-alkyl-O—C1-C24-alkyl (linear and branched), —C1-C24 alkyl morpholino, —C1-C24 alkyl piperidino, —C1-C24 alkyl piperazino, —C1-C24 alkyl-piperazino-N-alkyl, as well as cosmetic or dermatological preparations having an effective content of one or more alkylamidothiazoles, as well as the use thereof for the cosmetic or dermatological treatment and/or prophylaxis of undesired skin pigmentation.