Enhanced nucleic acid constructs for eukaryotic gene expression
US9534234B2 · kind B2 · utility
22Cited by
3References
6Claims
0Family size
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Key dates
| Filing date | Apr 9, 2015 |
| Grant date | Jan 3, 2017 |
| Priority date | — |
| Expiry date | Apr 9, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors further comprise novel transposons and transposases that further improve expression. Further disclosed are vectors that can be used in a gene transfer system for stably introducing nucleic acids into the DNA of a cell. The gene transfer systems can be used in methods, for example, but not limited to, gene expression, gene therapy, insertional mutagenesis, or gene discovery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.