Mining biological networks to explain and rank hypotheses
US9536193B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2015 |
| Grant date | Jan 3, 2017 |
| Priority date | — |
| Expiry date | Dec 9, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B5/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
An approach is provided to identify important paths in a biological relationship graph for exploration by researchers. In the approach, a biological meaningfulness analysis is performed on the biological relationship graph that has a number of paths through the graph formed by a number of connected nodes. The biological meaningfulness analysis is based on a process similarity calculation of gene ontologies of the nodes in the paths and a contextual similarity calculation of word occurrences from documents in a corpus where a reference to the respective nodes are found. A biological interestingness analysis is also performed on the biological relationship graph. The paths are screened based on the meaningfulness analysis and the interestingness analysis. The screened data is displayed to the user.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.