Orally dissolving thin films containing allergens and methods of making and use
US9539334B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 17, 2013 |
| Grant date | Jan 10, 2017 |
| Priority date | — |
| Expiry date | May 17, 2033 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29L2007/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a thin mucoadhesive sublingual film composition which provides improved allergen delivery and efficacy at a smaller dose while prolonging the contact time between the allergen and oral antigen presenting cells (APCs), and therefore minimizing the risk of systemic side effects. The thin film compositions of the present invention are also easier to standardize, and removes any need for measuring allergen doses at the physician's office, and which allows for a simplified dosing schedule. Methods of making the thin film compositions and methods for their use are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.