Substituted pyrimidine compounds

US9540349B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Antonio Nardi · Gambellara, IT
• Florian Jakob · Aachen, DE
• Ingo Konetzki · Warthausen, DE
• Tobias Craan · Niedernberg, DE
• Christian Hesslinger · Zoznegg, DE

Key dates

• Filing date: Jul 15, 2015
• Grant date: Jan 10, 2017
• Expiry date: Jul 15, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel substituted pyrimidine compounds of general formula (I)in which the chemical groupings, substituents, variables and indices are as defined in the description, and to their use as medicaments, in particular as medicaments for the treatment of conditions and diseases that can be treated by inhibition of the PDE4 enzyme.