Patent · US Active

Compounds having a protective activity against toxins with intracellular activity

US9540356B2 · kind B2 · utility

1Cited by

0References

12Claims

0Family size

Assignees

COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · FR
INSTITUT CURIE · FR
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR

Inventors

Daniel Gillet · Paris, FR
Julien Barbier · San Francisco, US
Ludger Johannes · Courbevoie, FR
Jean-Christophe Cintrat · Igny, FR
Romain Noel · Villeurbanne, FR

Key dates

Filing date	Oct 18, 2013
Grant date	Jan 10, 2017
Priority date	—
Expiry date	Oct 18, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention concerns a new family of 2,3-dihydroquinazolin-4(1H)-one compounds of general formula (I), and the use thereof as inhibitors of the toxic effects of toxins with intracellular activity, such as ricin or Shiga toxin, for example, using retrograde transport to intoxicate cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.