Use of kinase inhibitors to increase the susceptibility of gram positive bacteria to beta lactam antibiotics
US9540369B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Apr 24, 2015 |
| Grant date | Jan 10, 2017 |
| Priority date | — |
| Expiry date | Apr 24, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods of using certain kinase inhibitors for treating Gram positive bacterial infections are disclosed. When co-administered with a β-lactam antibiotic, the disclosed compounds increase the susceptibility of infectious Gram positive bacteria to the β-lactam antibiotic.The disclosed kinase inhibitors have either of the general formulas:or the specific formula:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.