6-arylamino pyridone carboxamide as MEK inhibitors
US9540396B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Nov 1, 2011 |
| Grant date | Jan 10, 2017 |
| Priority date | — |
| Expiry date | Jul 20, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly-morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.