Optimization of alginate encapsulation of islets for transplantation

US9540630B2 · kind B2 · utility

Assignee

• Beta-O2 Technologies Ltd. · IL

Inventors

• Uriel Barkai · Ofakim, IL
• Avi Rotem · Netanya, IL
• Dimitry Azarov · Netanya, IL
• Tova Neufeld · Modiin-Maccabim-Reut, IL
• Zohar Gendler · Zichron Ya'akov, IL

Key dates

• Filing date: Sep 16, 2009
• Grant date: Jan 10, 2017
• Expiry date: Jul 17, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2400/18
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Apparatus is provided, including a plurality of islets, and a hydrogel configured to macroencapsulate the plurality of islets. The hydrogel is implantable in a subcapsular space (21) of a kidney (22) of a subject and is shaped to define a planar configuration. Other applications are also described.