Patent · US Active

Multi-photon absorption for femtosecond micromachining and refractive index modification of tissues

US9545340B1 · kind B1 · utility

28Cited by

11References

27Claims

0Family size

Assignee

University of Rochester · US

Inventors

Wayne H. Knox · Rochester, US
Krystel R. Huxlin · Rush, US
Li Ding · Hefei, CN

Key dates

Filing date	Sep 9, 2008
Grant date	Jan 17, 2017
Priority date	—
Expiry date	Nov 28, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61F2009/0088
WIPO fieldMedical technology
WIPO sectorInstruments

Abstract

By adapting femtosecond micromachining approaches developed in hydrogels, we can perform Intra-tissue Refractive Index Shaping (IRIS) in biological tissues. We reduced femtosecond laser pulse energies below the optical breakdown thresholds to create grating patterns that are associated with a change in the refractive index of the tissue. To increase two-photon absorption, we used a two (or more)-photon-absorbing chromophore.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.