Patent · US Active

Pharmaceutical compositions comprising 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-y1)-1H-benzimidazol-2-y1]-1H-quinolin-2-one lactate monohydrate

US9545402B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Jeewan Thakur · Basel, CH
Zhihui Qiu · Bound Brook, US

Key dates

Filing date	Jun 29, 2011
Grant date	Jan 17, 2017
Priority date	—
Expiry date	Jan 1, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical composition for oral administration comprising 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one monolactate monohydrate, a filler in an amount of 15 to 70% by weight, a disintegrant in an amount of less than 15% by weight, a glidant and/or a lubricant in an amount of 0.1 to 10% by weight wherein the amounts by weight are based on the total weight of the composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.