Chemokine CXCR4 receptor modulators and uses related thereto

US9545403B2 · kind B2 · utility

Assignee

• EMORY UNIVERSITY · US

Inventors

• Lawrence Wilson · Mason, US
• John Wiseman · Atlanta, US
• Dennis C. Liotta · Atlanta, US
• Michael G. Natchus · Alpharetta, US

Key dates

• Filing date: Feb 17, 2015
• Grant date: Jan 17, 2017
• Expiry date: Feb 17, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing CXCR4 related conditions, typically prevention or treatment of viral infections such as HIV or for managing cancer.