Substituted quinazolin-4-ones for inhibiting ubiquitin specific protease 7
US9546150B2 · kind B2 · utility
26Cited by
5References
23Claims
0Family size
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Key dates
| Filing date | Aug 29, 2012 |
| Grant date | Jan 17, 2017 |
| Priority date | — |
| Expiry date | Aug 29, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to quinazolin-4-one compounds of formula (I′), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.