Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US9546213B2 · kind B2 · utility
5Cited by
97References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 2011 |
| Grant date | Jan 17, 2017 |
| Priority date | — |
| Expiry date | Mar 14, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient's survivability or quality of life will preferably be improved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.