Peptide-hydrogel composite

US9546235B2 · kind B2 · utility

Assignee

• The University of Sydney · AU

Inventors

• Fariba Dehghani · Rathdowney, AU
• Anthony Steven Weiss · Sydney, AU
• Hua Wei · Sydney, AU
• Suzanne Marie Mithieux · Sydney, AU
• Ali Fathi · Parramatta, AU

Key dates

• Filing date: Dec 19, 2012
• Grant date: Jan 17, 2017
• Expiry date: Jan 30, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F220/283
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to polymers, especially polymers useful as hydrogels, and to use of hydrogels for repair or restoration of tissue. In particular, the polymers and hydrogels of the present invention can be used for the repair or restoration of cartilage, especially articular cartilage. The polymers comprise at least a monomer for binding water, a monomer for imparting mechanical properties and a monomer for binding to an extracellular protein. The hydrogels comprise a polymer comprising at least a monomer for binding water and a monomer for binding to an extracellular protein. Crosslinking polymers by binding of said extra-cellular matrix protein forms hydrogels.