Patent · US Active

Nanopore sequencing using n-mers

US9546400B2 · kind B2 · utility

105Cited by

15References

15Claims

0Family size

Assignee

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

Stephen Turner · Menlo Park, US
Benjamin Flusberg · Atlanta, US

Key dates

Filing date	Sep 13, 2013
Grant date	Jan 17, 2017
Priority date	—
Expiry date	Feb 4, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2565/631
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to devices and methods for nanopore sequencing. The invention provides for using the signals from n-mers to provide sequence information, for example where the system has less than single base resolution. The invention includes arrays of nanopores having incorporated electronic circuits, for example, in CMOS. In some cases, the arrays of nanopores comprise resistive openings for isolating the electronic signals for improved sequencing. Methods for controlling translocation of through the nanopore are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.