Process for treprostinil salt preparation
US9550716B2 · kind B2 · utility
1Cited by
12References
34Claims
0Family size
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Key dates
| Filing date | Dec 22, 2011 |
| Grant date | Jan 24, 2017 |
| Priority date | — |
| Expiry date | Aug 27, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/43
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a process for preparing a treprostinil salt. The process involves the step of dissolving treprostinil in a water-miscible organic solvent to form a treprostinil solution. The treprostinil solution is reacted with an aqueous basic solution containing an alkali metal cation to form treprostinil salt. Allowing crystallization of the treprostinil salt to take place, and then collecting the treprostinil salt formed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.