Isolation and functional identification of cells
US9550978B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 11, 2011 |
| Grant date | Jan 24, 2017 |
| Priority date | — |
| Expiry date | Jul 7, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/585
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for tagging, identifying and isolating a target cell, wherein the cell is contacted with a capture compound comprising a small molecule moiety, for example a pharmaceutical drug molecule, capable of selectively binding with the cell surface of the target cell, and a function that is capable to covalently or quasi-covalently bind to a surface as a marker or tagging function. In some embodiments the capture compound also includes a photoactivatable reactivity function. The capture compound attaches to a particle that mediates identification or isolation of the tagged cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.