Method for nucleic acid detection using voltage enhancement
US9551026B2 · kind B2 · utility
6Cited by
77References
24Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 27, 2011 |
| Grant date | Jan 24, 2017 |
| Priority date | — |
| Expiry date | Dec 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6825
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods are provided for carrying out DNA sequencing on a device having upper and lower conductive layers separated by an insulative layer. Holes in the upper conductive layer create discrete attachment sites for DNA fragments. Voltage is applied to the surface to control affinity between the attachment sites and the DNA fragments, and to compact the DNA fragments for discrete optical detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.