Compositions and methods for detecting nitration of PKG-1α and methods of use thereof
US9551711B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Sep 30, 2014 |
| Grant date | Jan 24, 2017 |
| Priority date | — |
| Expiry date | Mar 4, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2440/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Antibodies for detecting nitration of nitrotyrosine 247 PKG-1α and antibodies for detecting nitrotyrosine 425 of PKG-1α are disclosed. Methods of detecting nitrotyrosine 247 PKG-1α and nitrotyrosine 425 of PKG-1α, and uses thereof are also disclosed for identification and diagnosis or phenotypes, pathologies, diseases and disorders associated with protein nitration of PKG-1α are also disclosed. In a preferred embodiment, one or more of the disclosed antibodies is used in the disclosed methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.