Bone matrix compositions having nanoscale textured surfaces

US9554920B2 · kind B2 · utility

Assignee

• Warsaw Orthopedic, Inc.

Inventors

• Guobao Wei · Milltown, US
• Keyvan Behnam · Simi Valley, US
• Nanette Forsyth · Bayville, US

Key dates

• Filing date: Nov 10, 2008
• Grant date: Jan 31, 2017
• Expiry date: Jan 28, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/40
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Bone matrix compositions having nanoscale textured surfaces and methods for their production are provided. In some embodiments, bone matrix is prepared for implantation and retains nanoscale textured surfaces. In other embodiments, nanostructures are imparted to bone matrix wherein collagen fibrils on the surface of the bone matrix have been compromised, thus imparting a nanoscale textured surface to the bone matrix. Generally, these methods may be applied to mineralized or demineralized bone including partially or surface demineralized bone.