Patent · US Active

Trilayer coated pharmaceutical packaging

US9554968B2 · kind B2 · utility

17Cited by
621References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 11, 2014
Grant dateJan 31, 2017
Priority date
Expiry dateJun 9, 2035

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/042
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An article is described including an article surface and a coating set comprising a tie coating or layer of SiOxCy or Si(NH)xCy applied to the article surface, a barrier coating or layer of SiOx, and a pH protective layer of SiOxCy or Si(NH)xCy. The respective coatings or layers can be applied by chemical vapor deposition of a polysiloxane or polysilazane precursor in the presence of oxygen. Examples of such an article are a prefilled thermoplastic syringe or thermoplastic pharmaceutical vial with a coated interior portion containing a pharmaceutical preparation or other fluid with a pH of 4 to 8, alternatively 5 to 9. The barrier coating or layer prevents oxygen from penetrating into the thermoplastic syringe or vial, and the tie coating or layer and pH protective coating or layer together protect the barrier layer from the contents of the syringe or vial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.