Patent · US Active

Oral solid formulation of compound anti-tubercular drug and preparation method thereof

US9555003B2 · kind B2 · utility

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1References
8Claims
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Key dates

Filing dateApr 10, 2012
Grant dateJan 31, 2017
Priority date
Expiry dateAug 13, 2032

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride. The compound oral solid preparation is a coated tablet with coated core or a coated three-layer tablet, wherein the two active ingredients rifampicin and isoniazid do not come to contact with each other directly. The compound oral solid preparation not only improves the stability of the compound preparation, but also improves the bioavailability of rifampicin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.