Oral solid formulation of compound anti-tubercular drug and preparation method thereof
US9555003B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2012 |
| Grant date | Jan 31, 2017 |
| Priority date | — |
| Expiry date | Aug 13, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride. The compound oral solid preparation is a coated tablet with coated core or a coated three-layer tablet, wherein the two active ingredients rifampicin and isoniazid do not come to contact with each other directly. The compound oral solid preparation not only improves the stability of the compound preparation, but also improves the bioavailability of rifampicin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.