Binding ligand linked drug delivery conjugates of tubulysins
US9555139B2 · kind B2 · utility
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127References
15Claims
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Key dates
| Filing date | Mar 13, 2008 |
| Grant date | Jan 31, 2017 |
| Priority date | — |
| Expiry date | Jun 15, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06078
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compounds, pharmaceutical compositions and methods for treating pathogenic cell populations. The compounds described herein include conjugates of tubulysins and vitamin receptor binding ligands. The conjugates also include a releasable bivalent linker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.