Nanopore-based sequencing with varying voltage stimulus
US9557294B2 · kind B2 · utility
22Cited by
11References
20Claims
0Family size
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Key dates
| Filing date | Dec 19, 2014 |
| Grant date | Jan 31, 2017 |
| Priority date | — |
| Expiry date | Jun 12, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0421
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of analyzing a molecule in a nanopore is disclosed. A voltage is applied across a nanopore that is inserted in a membrane by coupling the nanopore to a voltage source. The nanopore is decoupled from the voltage source. After the decoupling, a rate of decay of the voltage across the nanopore is determined. A molecule in the nanopore is distinguished from other possible molecules based on the determined rate of decay of the voltage across the nanopore.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.