Fluoromethyl-substituted pyrrole carboxamides as CaV2.2 calcium channel blockers

US9562036B2 · kind B2 · utility

Assignee

• GRÜNENTHAL GMBH · DE

Inventors

• Melanie Reich · Aachen, DE
• Stefan Schunk · Aachen, DE
• Florian Jakob · Aachen, DE
• Henning Steinhagen · Pocking, DE
• Nils Damann · Bad Mergentheim, DE
• Michael Haurand · Aachen, DE
• Marc Rogers · St Ives, GB
• Kathy MacKenzie · Hertford, GB

Key dates

• Filing date: Jun 17, 2016
• Grant date: Feb 7, 2017
• Expiry date: Jun 17, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.