Heterocyclic pyridone compound, and intermediate, preparation method and use thereof
US9562060B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 28, 2012 |
| Grant date | Feb 7, 2017 |
| Priority date | — |
| Expiry date | Nov 22, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a heterocyclic pyridone compound represented by General Formula (I), where the heterocyclic pyridone compound is used as a tyrosine kinase inhibitor, and particularly a c-Met inhibitor. The present invention also relates to intermediates for preparing heterocyclic pyridone compound and a preparation method. The present invention further relates to a pharmaceutical composition containing the heterocyclic pyridone compound as an active ingredient, and a use of the pharmaceutical composition in treatment of diseases associated with tyrosine kinase c-Met, especially cancer associated with c-Met, as a medicament.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.