Peptidyl arginine deiminase 1 and/or 3 activator compounds in the epidermis and uses thereof
US9566222B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2012 |
| Grant date | Feb 14, 2017 |
| Priority date | — |
| Expiry date | Apr 11, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.