Artificial tissue constructs comprising alveolar cells and methods for using the same
US9566250B2 · kind B2 · utility
1Cited by
12References
20Claims
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Key dates
| Filing date | Jan 13, 2014 |
| Grant date | Feb 14, 2017 |
| Priority date | — |
| Expiry date | Feb 22, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises artificial tissue constructs that serve as in vitro models of mammalian lung tissue. The artificial tissue constructs of the present invention comprise functionally equivalent in vitro tissue scaffolds that enable immunophysiological function of the lung. The constructs can serve as novel platforms for the study of lung diseases (e.g., interstitial lung diseases, fibrosis, influenza, RSV) as well as smoke- and smoking-related diseases. The artificial tissue constructs of the present invention comprise the two components of alveolar tissue, epithelial and endothelial cell layers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.