Methods of using phthalazinone ketone derivatives

US9566277B2 · kind B2 · utility

Assignee

• JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD · CN

Inventors

• Peng Cho Tang · Moraga, US
• Xin Li · Shanghai, CN
• Xiangqin Li · Shanghai, CN
• Yang Chen · Shanghai, CN
• Bin Wang · Beijing, CN
• Zhe Zhu · Shanghai, CN

Key dates

• Filing date: Feb 5, 2016
• Grant date: Feb 14, 2017
• Expiry date: Feb 5, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof are described.