Patent · US Active

Positively charged polysaccharides for RNA transfection

US9566346B2 · kind B2 · utility

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12Claims
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Key dates

Filing dateFeb 5, 2014
Grant dateFeb 14, 2017
Priority date
Expiry dateFeb 5, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2320/32
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A complex includes RNA and a positively charged modified polysaccharide selected from starch, amylose, amylopectin, galactan, chitosan, or dextrin. The complex can be formed into a pharmaceutical composition. The complex can be used in methods for RNA transfection, gene therapy and treatment of a disease, disorder or condition. The positively charged modified polysaccharide can be used in connection with RNA transfection into cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.