Multiple-layer immune barrier for donor cells
US9566366B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Aug 10, 2016 |
| Grant date | Feb 14, 2017 |
| Priority date | — |
| Expiry date | Aug 10, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/915
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system is provided, including a plurality of donor cells and a first alginate structure that encapsulates the plurality of donor cells. The first alginate structure has a guluronic acid concentration of between 64% and 74%. The system additionally includes a second alginate structure that surrounds the first alginate structure, the second alginate structure having a mannuronic acid concentration of between 52% and 60%. A selectively-permeable membrane is coupled at least in part to the second alginate structure. Other embodiments are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.