Patent · US Active

Multicomponent crystalline system comprising nilotinib and selected co-crystal formers

US9567317B2 · kind B2 · utility

6Cited by

4References

21Claims

0Family size

Assignee

BASF SE

Inventors

Tiziana Chiodo · Mannheim, DE
Andreas Hafner · Gelterkinden, CH
Tobias Hintermann · Therwil, CH
Beate Salvador · Ellerstadt, DE
Martin Szelagiewicz · Münchenstein, CH
Fritz Blatter · Reinach, CH
Eva Roedel · Basel, CH
Marcus Vossen · Schifferstadt, DE

Key dates

Filing date	Oct 16, 2013
Grant date	Feb 14, 2017
Priority date	—
Expiry date	Oct 16, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to crystalline materials comprising nilotinib and a carboxylic acid, carboxylic acid ester, carboxylic acid amide or sulfonic acid as a co-crystal former, and to pharmaceutical compositions comprising said materials. The invention also relates to processes for preparing said crystalline materials and to methods of using said crystalline materials to treat a disease condition in which tyrosine kinase inhibition is beneficial.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.