Enhanced AAV-mediated gene transfer for retinal therapies
US9567376B2 · kind B2 · utility
42Cited by
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6Claims
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Assignee
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Key dates
| Filing date | Feb 7, 2014 |
| Grant date | Feb 14, 2017 |
| Priority date | — |
| Expiry date | Feb 7, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are capsid proteins and adeno-associated viruses capable of targeting various types of ocular cells including bipolar and horizontal cells. Also described herein are methods of treating various ocular disorders in a subject in need thereof by administering to the subject an effective concentration of a composition comprising the recombinant adeno-associated virus (AAV) of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.