Anti-vasa antibodies, and methods of production and use thereof
US9567404B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jul 6, 2016 |
| Grant date | Feb 14, 2017 |
| Priority date | — |
| Expiry date | Jul 6, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/914
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Anti-VASA antibodies (mAbs), particularly humanized mAbs that specifically bind to VASA with high affinity, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-VASA mAbs are provided. The disclosure also provides nucleic acid molecules encoding the anti-VASA mAbs, expression vectors, host cells, methods for making the anti-VASA mAbs, and methods for expressing the anti-VASA mAbs. Finally, methods of using the anti-VASA mAbs to isolate and/or purify cells expressing VASA are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.