Skin permeation device for analyte sensing or transdermal drug delivery
US9572527B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 22, 2013 |
| Grant date | Feb 21, 2017 |
| Priority date | — |
| Expiry date | Jan 22, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/328
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Devices, systems, kits and methods for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip, (iii) a feedback control mechanism, (iv) two or more electrodes, and (v) an electrical motor. The feedback control mechanism may be an internal feedback control mechanism or an external feedback control. The kit contains the controlled abrasion-device, one or more abrasive tips, optionally with a wetting fluid. The method for increasing the skin's permeability requires applying the controlled abrasion device to a portion of the skin's surface for a short period of time, until the desired level of permeability is reached. Then the abrasion device is removed, and a drug delivery composition or device or an analyte sensor is applied to the treated site.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.